The official Team Kentucky source for information concerning COVID-19

Team Kentucky - Kentucky Cabinet for Health and Family Services - Department for Public Health

Learn about the safe, effective COVID-19 vaccines and find where to get vaccinated at

What is a monoclonal antibody?

A monoclonal antibody is a laboratory-made protein that mimics your immune system’s ability to fight off harmful viruses that can cause disease. It is a treatment that may make your COVID-19 disease less severe and hasten your recovery. Monoclonal antibody treatment is not a substitute for a COVID-19 vaccine.

Who can receive a monoclonal antibody treatment?

If you test positive for COVID-19 and meet the following criteria, you may be eligible to receive a monoclonal antibody treatment:

  • Not hospitalized
  • 12 years of age or older and weigh at least 88 lbs.
  • Have mild to moderate symptoms of COVID-19 that started less than 10 days ago
  • At higher risk for severe COVID-19 infection due to any of the below:
    • Age 65 years or older
    • Overweight or obese (may include a Body Mass Index (BMI) of > 25 for adults or > 85th percentile for children)
    • Pregnant
    • Diabetes (Type I or Type II)
    • Chronic kidney disease
    • Immunosuppressive disease or taking medication that suppresses the immune system
    • Cardiovascular disease (including congenital heart disease) or hypertension (high blood pressure)
    • Chronic lung disease such as chronic obstructive pulmonary disease (COPD), moderate to severe asthma, cystic fibrosis, or pulmonary hypertension
    • Sickle cell disease
    • Neurodevelopmental disorders such as cerebral palsy
    • Medical-related technological dependence (tracheostomy, gastrostomy, or ventilation not related to COVID)

A physician referral or clinician evaluation is necessary to receive monoclonal antibody treatment. If you believe you meet the criteria above, reach out to your healthcare provider to discuss this option or seek evaluation at a monoclonal antibody center that provides eligibility screenings.

Monoclonal Antibody Treatment

  • Fights Coronavirus with manufactured antibodies
  • Administered through IV infusion or multiple injections within 10 days of a positive COVID-19 test
  • May be out of pocket cost
  • Limited availability, short treatment window, & protections for less than 90 days
  • Under FDA Emergency Use Authorization (EUA)
  • 70-85% effective in reducing severe disease, hospitalization, or death

COVID-19 Vaccine

  • Defends against Coronavirus with your own immune system and antibodies
  • Administered in one or two injections before infection
  • No out of pocket cost
  • Readily available, nearly all persons 12 and older eligible, & protection for more than 8 months
  • FDA approved and/or Under EUA
  • Greater than 99% effective in reducing severe disease, hospitalization, or death

Centers for Disease Control and Prevention